Principal Investigator

Hanrui Zhang, MB PhD

Hanrui_Zhang

Herbert Irving Assistant Professor of Medical Sciences

Email: hz2418@cumc.columbia.edu

ORCID iD iconhttps://orcid.org/0000-0001-8655-938X

Dr. Hanrui Zhang is a macrophage biologist. She completed her PhD training in 2011 at the University of Missouri. Her graduate work centered on the crosstalk between immune cells and blood vessels in diabetes-associated vascular diseases. Her postdoctoral research at the University of Pennsylvania continued to address the mechanisms of cardiometabolic diseases focusing on macrophage lipid metabolism and inflammation using gene targeting in human induced pluripotent stem cells (iPSC) with differentiation to macrophages. Her laboratory at Columbia University Irving Medical Center seeks to understand the dynamic role of macrophages in cardiometabolic diseases with the aim of finding novel mechanisms and new treatments.

Hanrui is the Chair of the Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) — Women’s Leadership Committee, the American Heart Association (AHA). She is also a member of the ATVB Leadership Committee, and the ATVB Investigator-in-Training Award Committee. She is currently serving as the Technical Review Editor for the ATVB Journal.

Education & Training

 

Lab Members

Jianting Shi, MS

Research Specialist

My work focuses on exploring the functionality of myeloid cells and their roles in cardiometabolic diseases using genome-wide CRISPR screen and next-gen sequencing technologies.

Education & Training

Fang Li, PhD

Fang_Li

Postdoctoral Scientist, AHA Postdoctoral Fellow

ORCID iD iconhttps://orcid.org/0000-0001-9180-3615

I am interested in the functional interrogation of coronary artery disease-associated loci identified by human genome-wide association studies. My current work focuses on the role of lysosomal acid lipase in atherosclerosis.

Education & Training

Xun Wu, PhD

Xun_Wu

Postdoctoral Scientist, AHA Postdoctoral Fellow

ORCID iD iconhttps://orcid.org/0000-0002-0742-7459

Education & Training

Rebecca Moore

Research Specialist, Casual Position

Education & Training

Tyler Shern

Undergraduate Research Assitant, SRF (Science Research Fellow) and SURF Scholar, Columbia University 2025

Philip Ha

High School Student, Townsend Harris 2022

 

Lab Alumni

MS Student

Ziyi Wang, MS in Human Nutrition, Columbia University (09/2019-02/2021), Research Specialist (PT) in the lab (03/2021-07/2022).
Shamma Ali, MS in Human Nutrition, Columbia University (09/2020-09/2021)
Rebecca Moore, MS in Human Nutrition Columbia University (09/2020-04/2022)

Undergraduate Researchers

Eden Tilahun Teferi, Columbia College 2021 (09/2018-01/2019)
Raneem Hamad, Columbia College 2021 (09/2018-03/2020)
Eileen Moudou, Columbia College 2020 (01/2019-05/2019)
Yolanda Jean-Baptiste, BS, Fellow of the NERA Program (06/2019-07/2019)
Jeana Chun, BS, SURF Scholar, Columbia College 2022 (01/2019-05/2022)
Annie Rozenblyum, BS, Barnard College 2022 (01/2019-05/2022)

Columbia Data Science Institute (DSI) Scholars

Joey Zihui Gu, MS in Data Science, Columbia University (09/2018-12/2018)
Jiayi Shen, MS in Biostatistics, Columbia Univ. Mailman School of Public Health (03/2019-07/2019)
Jianyou Liu, MS in Biostatistics, Columbia Univ. Mailman School of Public Health (03/2019-07/2019)
Joy Hsu, MS in Biostatistics, Columbia Univ. Mailman School of Public Health (11/2019-05/2020) Neha Pusarla, MS in Data Science, Columbia Univ. (03/2021-06/2021)
Sophie Shan, BS in Statistics, CUSP Scholar, Columbia College 2022 (11/2019-09/2021)

Visting Scientists

Yujiao Meng, Visiting PhD Student, Beijing Univ. of Chinese Medicine (12/2019-03/2021).