Principal Investigator

Hanrui Zhang, MB PhD


Herbert Irving Assistant Professor of Medical Sciences


ORCID iD icon

linkedin LinkedIn   github Github

Dr. Hanrui Zhang is a macrophage biologist. She completed her PhD training in 2011 at the University of Missouri. Her graduate work centered on the crosstalk between immune cells and blood vessels in diabetes-associated vascular diseases. Her postdoctoral research at the University of Pennsylvania continued to address the mechanisms of cardiometabolic diseases focusing on macrophage lipid metabolism and inflammation using gene targeting in human induced pluripotent stem cells (iPSC) with differentiation to macrophages. Her laboratory at Columbia University Irving Medical Center seeks to understand the dynamic role of macrophages in cardiometabolic diseases with the aim of finding novel mechanisms and new treatments.

Hanrui is the Chair of the Women’s Leadership Committee, the Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) council of the American Heart Association (AHA). She is also a member of the ATVB Leadership Committee, and the ATVB Investigator-in-Training Award Committee. She is currently serving as the Technical Review Editor for the ATVB Journal.

Education & Training


Lab Members

Fang Li, PhD


Postdoctoral Scientist, AHA Postdoctoral Fellow, CDA Awardee

ORCID iD icon

I am interested in the functional interrogation of coronary artery disease-associated loci identified by human genome-wide association studies. My current work focuses on the role of lysosomal acid lipase in atherosclerosis.

Education & Training

Xun Wu, PhD


Postdoctoral Scientist, AHA Postdoctoral Fellow

ORCID iD icon

Education & Training

Mazal Zebak, BA


linkedin LinkedIn  

Research Specialist

Education & Training

Rehet Chugh

MS student in Human Nutrition, Columbia University, New York City, NY.

Education & Training

Tyler Shern

Undergraduate Research Assitant, SRF (Science Research Fellow) and SURF Scholar, Columbia University 2025

Philip Ha

Undergraduate Research Assistant, Macaulay Honors College at Hunter College 2026


Lab Alumni

Research Specialist

Jianting Shi, MS, Research Specialist (07/2018-08/2023) –> Data Analyst

MS Student

Ziyi Wang, MS in Human Nutrition, Columbia University (09/2019-02/2021), Research Specialist (PT, 03/2021-07/2022) –> PharmD program
Shamma Ali, MS in Human Nutrition, Columbia University (09/2020-09/2021)
Rebecca Moore, MS in Human Nutrition Columbia University (09/2020-09/2022), Research Specialist (Casual, 09/2022-12/2022)

Undergraduate Researchers

Eden Tilahun Teferi, Columbia College 2021 (09/2018-01/2019)
Raneem Hamad, Columbia College 2021 (09/2018-03/2020)
Eileen Moudou, Columbia College 2020 (01/2019-05/2019)
Yolanda Jean-Baptiste, BS, Fellow of the NERA Program (06/2019-07/2019)
Jeana Chun, BS, SURF Scholar, Columbia College 2022 (01/2019-05/2022)
Annie Rozenblyum, BS, Barnard College 2022 (01/2019-05/2022) –> MD program

Columbia Data Science Institute (DSI) Scholars

Joey Zihui Gu, MS in Data Science, Columbia University (09/2018-12/2018)
Jiayi Shen, MS in Biostatistics, Columbia Univ. Mailman School of Public Health (03/2019-07/2019) –> PhD program
Jianyou Liu, MS in Biostatistics, Columbia Univ. Mailman School of Public Health (03/2019-07/2019)
Joy Hsu, MS in Biostatistics, Columbia Univ. Mailman School of Public Health (11/2019-05/2020)
Neha Pusarla, MS in Data Science, Columbia Univ. (03/2021-06/2021)
Sophie Shan, BS in Statistics, CUSP Scholar, Columbia College 2022 (11/2019-09/2021) –> PhD program

Visting Scientists

Yujiao Meng, Visiting PhD Student, Beijing Univ. of Chinese Medicine (12/2019-03/2021) –> Instructor

High School Students

Philip Ha, Townsend Harris 2022 (03/2020-08/2022) –> Undergraduate Research Assistant in the lab