Principal Investigator

Hanrui Zhang, MB PhD


Assistant Professor of Medicine

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Dr. Hanrui Zhang is a macrophage biologist and cardiovascular physiologist. She completed her PhD training in 2011 at the University of Missouri. Her graduate work centered on the crosstalk between immune cells and blood vessels in diabetes-associated vascular diseases. Her postdoctoral research at the University of Pennsylvania continued to address the mechanisms of cardiometabolic diseases focusing on macrophage lipid metabolism and inflammation using gene targeting in human induced pluripotent stem cells (iPSC) with differentiation to macrophages. Her laboratory at Columbia University Irving Medical Center seeks to understand the dynamic role of macrophages in cardiometabolic diseases with the aim of finding novel mechanisms and new treatments. (Email:

Hanrui is a member of the American Heart Association (AHA), Council on Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) — Women’s Leadership Committee.

Education & Training


Lab Members

Jianting Shi, MS

Research Specialist

My work focuses on exploring the functionality of myeloid cells and their roles in cardiometabolic diseases using genome-wide CRISPR screen and next-gen sequencing technologies. (Email:

Education & Training

Fang Li, PhD


Postdoctoral Scientist, AHA Postdoctoral Fellow

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I am interested in the functional interrogation of coronary artery disease-associated loci identified by human genome-wide association studies. My current work focuses on the role of lysosomal acid lipase in atherosclerosis. (Email:

Education & Training

Xun Wu, PhD


Postdoctoral Scientist, Berrie Diabetes Scholar

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Education & Training

Raneem Hamad

Undergraduate Research Assistant, Columbia College 2021

Jeana Chun

Undergraduate Research Assistant, SURF Scholar, Columbia College 2022

Annie Rozenblyum

Undergraduate Research Assistant, Barnard College 2022

Sufang Li, PhD

Visiting Postdoctoral Fellow, Beijing University Renmin Hospital

Yujiao Meng

Visiting PhD Student, CSC Awardee, Beijing University of Chinese Medicine

Joy Hsu

Data Science Institute Scholar, MS in Biostatistics, Columbia University Mailman School of Public Health

Sophie Shan

Data Science Institute Scholar, BS in Statistics, CUSP Scholar, Columbia College 2022

Ziyi Wang

MS student in Human Nutrition, Institute of Human Nutrition, Columbia University.

Mazen Alsafi

Undergraduate Research Assistant, Columbia College 2023

Philip Ha

High School Student, Townsend Harris 2022


Lab Alumni

Undergraduate Researchers

Eileen Moudou, Columbia College 2020 (01/2019-05/2019)
Yolanda Jean-Baptiste, BS, Fellow of the NERA Program (06/2019-07/2019)

Columbia Data Science Institute (DSI) Scholars

Joey Zihui Gu, MS in Data Science, Columbia University (09/2018-12/2018)
Jiayi Shen, MS in Biostatistics, Columbia University Mailman School of Public Health (03/2019-07/2019)
Jianyou Liu, MS in Biostatistics, Columbia University Mailman School of Public Health (03/2019-07/2019)