The goal of the Zhang laboratory is to elucidate the mechanisms and therapeutic implications of macrophage heterogeneity and plasticity in cardiometabolic diseases.

Dr. Zhang’s laboratory seeks to understand the dynamic role of macrophages in cardiometabolic diseases with the aim of finding novel mechanisms and new treatments. The laboratory applies technologies for high-throughput functional genomics, human iPSC and CRISPR gene editing, transgenic mouse models, human genetics, and a variety of cell and molecular techniques.

The main areas of research in the laboratory include: